A Novel Antagonist of the Immune Checkpoint Protein Adenosine A2a Receptor Restores Tumor-Infiltrating Lymphocyte Activity in the Context of the Tumor Microenvironment

BACKGROUND: Therapeutic strategies targeting immune checkpoint proteins have led to significant responses in patients with various tumor types.The success of these studies has led to the development of various antibodies/inhibitors for the Sofa Cushions different checkpoint proteins involved in immune evasion of the tumor.Adenosine present in high

read more



Fuzzy ELM-based optimal spectrum sensing in CR-IoT network

In the Beds Internet of Things (IoT), spectral efficiency is a major challenge since many sensors and devices are placed widely throughout the network.Spectrum scarcity issues have been a concern for the Internet of Things since its inception.The use of Cognitive Radio (CR) technology is thought to be a potential remedy.Two of the problems that CR

read more